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YK-11 Sarms powder

Products Name: YK-11 Biological half-life: 24~36 Hours
Other name: YK-11 Content: 99%
CAS NO: 1370003-76-1 Quality standard: Enterprise standard
Molecular Formula: C25H34O6 Apperance:  White to Off-White Powder
Molecular weight: 430.541 Storage: Cool, dry and ventilated
Minimum Order Quantity: 10g, 1kg Price: 1~3 USD
Express Delivery: EMS, HKEMS, DHL, Fedex Payment Terms: T/T, Western Union, MoneyGram, Bitcoin
Delivery Time: 3~10work days after payment Stock: China, USA, UK


YK-11 is a synthetic, steroidal selective androgen receptor modulator (SARM).
It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR.The drug has anabolic activity in vitro in C2C12 myoblasts and shows greater potency than dihydrotestosterone (DHT) in this regard.

YK-11 induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as growth differentiation factor as a myokine, a protein produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass.
YK11 can be as good as testosterone in terms of muscle strengthening, but minus the detrimental side effects.

Supply high quality YK-11 Sarm powder

YK11 is a partial agonist of the androgen receptor with a greater effect on increasing follistatin than DHT does (Kano et all 2013 Selective Androgen Receptor Modulator, YK11, Regulates Myogenic Differentiation of C2C12 Myoblasts by Follistatin Expression). What follistatin does is it inhibits the action of myostatin. Myostatin inhibits the actions of Myf5, MyoD, and myogenin. Myf5, MyoD, and myogenin induces muscle growth. This is excellent news for us but there is a negative aspect of YK11 being a partial agnonist of the androgen receptor. YK11 may inhibit testosterone and DHT from acting on the androgen receptor since it will compete for binding at the androgen receptor with testosterone and DHT. This is something to consider if running YK11 as there is the risk that running DHT compounds and/or testosterone or other androgens may reduce their effectiveness since YK11 will be competing with and taking up some of the androgen receptors. In a low testosterone and/or low DHT state however, YK11 would be beneficial as you have less of a risk for androgen receptor saturation. With that said, even though there is a risk of YK11 being a antiandrogen and that it may be less anabolic than DHT and/or testosterone, the effects on follistatin may counter this potential drawback. This is something which should be considered when deciding to run YK11 with other androgens.


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Sarms Powder, YK-11

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